mutations in cep290 (Staples)
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Mutations In Cep290, supplied by Staples, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Article Title: The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone
Journal: Molecular Biology of the Cell
doi: 10.1091/mbc.E13-09-0526
Figure Legend Snippet: Cep290 recruitment to centrosomal satellites and basal bodies depends on SSX2IP in RPE-1 cells. (a) Cells were transfected with control or SSX2IP siRNA and stained for Cep290 and γ-tubulin using indirect immunofluorescence. (b) Average projection of 50 cells immunostained as shown in a. Centering of single images before projection was based on the γ-tubulin signal. (c, d) Quantification of signal intensities of Cep290 at the basal body (c) or in satellites (d) of cells transfected with control or SSX2IP siRNA. (c, d) Left (bars), mean values of averages ± SEM from three independent experiments ( n = 150) normalized to controls. Right (box-and-whiskers plots), quantification of a single representative experiment. * p < 0.05, ** p < 0.01, *** p < 0.001 (two-tailed Student's t test).
Techniques Used: Transfection, Control, Staining, Immunofluorescence, Two Tailed Test
Related Articles
Transfection:Article Title: The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone Article Snippet: Of importance, mutations in Cep290, also known as BBS14, were previously shown to correlate with several ciliopathies, including Bardet–Biedl syndrome, Meckel–Gruber syndrome, and Control:Article Title: The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone Article Snippet: Of importance, mutations in Cep290, also known as BBS14, were previously shown to correlate with several ciliopathies, including Bardet–Biedl syndrome, Meckel–Gruber syndrome, and Staining:Article Title: The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone Article Snippet: Of importance, mutations in Cep290, also known as BBS14, were previously shown to correlate with several ciliopathies, including Bardet–Biedl syndrome, Meckel–Gruber syndrome, and Immunofluorescence:Article Title: The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone Article Snippet: Of importance, mutations in Cep290, also known as BBS14, were previously shown to correlate with several ciliopathies, including Bardet–Biedl syndrome, Meckel–Gruber syndrome, and Two Tailed Test:Article Title: The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone Article Snippet: Of importance, mutations in Cep290, also known as BBS14, were previously shown to correlate with several ciliopathies, including Bardet–Biedl syndrome, Meckel–Gruber syndrome, and Membrane:Article Title: The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone Article Snippet: Of importance, mutations in Cep290, also known as BBS14, were previously shown to correlate with several ciliopathies, including Bardet–Biedl syndrome, Meckel–Gruber syndrome, and |